In the pilot episode of the show, we start off by seeing a young couple who've lost their way through a series of ill-fated detours. At a dead-end, they come face-to-face with the horror that the government and the media have been trying to keep from the us all: the living dead plague that has begun to sweep across the East Coast. They lock themselves in their car and are quickly surrounded. That is, of course.......until the Zombie Hunters arrive! The group of professional slayers of the undead rescue the humans, make short business of the Zombies, and leave the shocked couple in their blood-soaked car.
But as we see next, this is just a glimpse into the future of the Zombie Hunters' world. What unfolds during the next five episodes are the early reactions to the plague, the spread of the undead through the city, the formation of the Hunter's Death Squad, the emotional and physical toll it takes on them, and how they all almost die during their first night out!
We also get to see into the mind of Billy Cassidy, one of the central figures of the story, who is looking for his missing girlfriend, Paramedic Judy Moskowitz. Will he find her before it's too late? Or has her fate already been sealed?